No. 18: Sidney and Caroline Kimmel
The couple donated $115-million to their foundation, most of which will go to Thomas Jefferson University for its medical school.
Mr. Wilson gave about $1-billion to his Ralph C. Wilson Jr. Foundation, which supports nonprofits in parts of New York State and Michigan.
The last living child of the philanthropist John D. Rockefeller Jr. gave $75-million to Rockefeller University.
No. 48: H.F. Gerry and Marguerite Lenfest
The couple donated more than $49-million to college scholarships and the American Revolution Center.
Rancher Jack Vanier, his wife, and three children gave $60-million to the Kansas State University Foundation.
No. 35: Kavitark and Vidjealatchoumy Shriram
The couple gave $61-million to Stanford University, where their daughters are students.
Dr. Eshelman gave $103-million to the University of North Carolina at Chapel Hill, most of it for the school of pharmacy.