No. 5: Sergey Brin and Anne Wojcicki
Mr. Brin and Ms. Wojcicki, both 39, gave about $190.1-million to their Brin Wojcicki Foundation, which supports a variety of causes.
Mr. Driehaus, 70, pledged $30-million to DePaul University for its College of Commerce, which has been renamed the Richard H. Driehaus College of Business.
No. 21 (tied): Jeff and Judy Henley
The Henleys pledged $50-million to the University of California at Santa Barbara.
Mr. Ellison, 68, gave slightly more than $45.6-million to his Ellison Medical Foundation to support biomedical research.